Compound Q&A
How is 2,4-Difluoro-3-methylbenzoic acid (CAS: 112857-68-8) typically synthesized?
Answer
2,4-Difluoro-3-methylbenzoic acid can be synthesized via the electrophilic fluorination of 3-methylbenzoic acid in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction is typically conducted in an inert solvent like dichloromethane. The yield is usually around 80-85%, and the selectivity for the 4-position fluorination is high.
About
CAS No
112857-68-8
English Name
2,4-Difluoro-3-methylbenzoic acid
Molecular Formula
C8H6F2O2
Molecular Weight
172.13 g/mol
SMILES
CC1=C(C=CC(=C1F)C(=O)O)F
InChIKey
OCJDCFUHHBCTFI-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
