Compound Q&A
How is 4-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one (CAS: 1086064-49-4) typically synthesized?
Answer
![4-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one](https://static.chemtradehub.com/structs/108/1086064-49-4-1974.webp "4-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one")
4-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one is typically synthesized via a condensation reaction between 2-bromopyridine and pyrrole. The process involves heating a mixture of the two reagents in the presence of a catalyst such as p-toluenesulfonic acid or trifluoromethanesulfonic acid under reflux. The yield can be improved by using anhydrous conditions and appropriate solvents like toluene or dimethylformamide.
About
CAS No
1086064-49-4
English Name
4-Bromo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Molecular Formula
C7H5BrN2O
Molecular Weight
213.03 g/mol
SMILES
O=C1Nc2c(C1)c(Br)ccn2
InChIKey
CVHDUJPKUBAWBD-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04
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