Compound Q&A

How is 7-Fluoro-1-methyl-1H-indole-2,3-dione (CAS: 875003-43-3) typically synthesized?

Answer

7-Fluoro-1-methyl-1H-indole-2,3-dione
7-Fluoro-1-methyl-1H-indole-2,3-dione is commonly synthesized via the reaction of indole with radioactive fluorine-18 or by the fluoroalkylation of indole derivatives. The synthesis often involves the use of a Lewis acid catalyst and proceeds with good selectivity. The yield of the product can be as high as 80% under optimized conditions.

About

English Name 7-Fluoro-1-methyl-1H-indole-2,3-dione
Molecular Formula C9H6FNO2
Molecular Weight 179.15 g/mol
SMILES O=C1N(C)C2=C(C=CC=C2F)C1=O
InChIKey XWTUHLYJQKEZSI-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12

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