Compound Q&A

How is 3-Bromo-5-(trifluoromethyl)-1H-pyrazole (CAS: 93608-11-8) typically synthesized?

Answer

3-Bromo-5-(trifluoromethyl)-1H-pyrazole
3-Bromo-5-(trifluoromethyl)-1H-pyrazole can be synthesized via a Swern oxidation of 5-(trifluoromethyl)-1H-pyrazole followed by bromination. The reaction typically involves the use of oxalyl chloride and dimethyl sulfoxide as the reagents, and the yield can reach up to 85%.

About

CAS No 93608-11-8
English Name 3-Bromo-5-(trifluoromethyl)-1H-pyrazole
Molecular Formula C4H2BrF3N2
Molecular Weight 214.97 g/mol
SMILES C1=C(NN=C1Br)C(F)(F)F
InChIKey ULONMXISWOZBAK-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12

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