Compound Q&A
How is N-Benzoyl-5'-O-[(3-methoxyphenyl)(4-methoxyphenyl)phenylmethyl]cytidine (CAS: 81246-76-6) typically synthesized?
Answer
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N-Benzoyl-5'-O-[(3-methoxyphenyl)(4-methoxyphenyl)phenylmethyl]cytidine is typically synthesized via a multi-step process involving protection of the cytidine, benzoylation, and subsequent coupling reactions. Commonly used catalysts include boron trifluoride etherate and triphenylphosphine. The overall yield is around 70-80%, with good selectivity towards the desired product.
About
CAS No
81246-76-6
English Name
N-Benzoyl-5'-O-[(3-methoxyphenyl)(4-methoxyphenyl)phenylmethyl]cytidine
Molecular Formula
C37H35N3O8
Molecular Weight
649.7 g/mol
SMILES
COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6)O)O
InChIKey
BAQYNHIPXQFDKH-FORCZIDESA-N
Last Updated: 2025-11-01 22:12
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