Compound Q&A
How is (3S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid (CAS: 790203-84-8) typically synthesized?
Answer
![(3S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid](https://static.chemtradehub.com/structs/790/790203-84-8-a175.webp "(3S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid")
(3S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid can be synthesized via a multi-step process involving protection of the amino group, formation of a trifluoromethylated phenyl ester, and subsequent deprotection to yield the desired product. Commonly, this involves the use of trifluoromethylated anhydrides as the fluorinating agent and amines as catalysts. The overall yield is typically around 70-80%.
About
CAS No
790203-84-8
English Name
(3S)-3-Amino-3-[4-(trifluoromethyl)phenyl]propanoic acid
Molecular Formula
C10H10F3NO2
Molecular Weight
233.19 g/mol
SMILES
C1=CC(=CC=C1C(CC(=O)O)N)C(F)(F)F
InChIKey
ABDRZHVLIRZFQO-QMMMGPOBSA-N
Last Updated: 2025-11-01 22:12
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