Compound Q&A

How is 1-(isocyanatomethyl)-4-methoxybenzene (CAS: 56651-60-6) typically synthesized?

Answer

1-(isocyanatomethyl)-4-methoxybenzene
1-(isocyanatomethyl)-4-methoxybenzene is typically synthesized by the reaction of 4-methoxybenzylamine with phosgene or carbon dioxide in the presence of a catalyst such as N,N-dimethylformamide (DMF). The process involves the formation of a carbamate intermediate, which is then hydrolyzed to yield the target compound. The yield is generally good, and the selectivity is high.

About

CAS No 56651-60-6
English Name 1-(isocyanatomethyl)-4-methoxybenzene
Molecular Formula C9H9NO2
Molecular Weight 163.18 g/mol
SMILES COC1=CC=C(C=C1)CN=C=O
InChIKey QRBHVARIMDDOOV-UHFFFAOYSA-N
Last Updated: 2025-11-01 22:12

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