Compound Q&A
How is 1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butanamine (CAS: 84467-54-9) typically synthesized?
Answer
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1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butanamine is usually synthesized via a multi-step process involving the coupling of 4-chlorophenylcyclobutylamine with 3-methyl-1-butanone under acidic conditions. The reaction typically proceeds with a yield of around 80%, and the use of a suitable catalyst like titanium(IV) isopropoxide can enhance the selectivity and yield. The product undergoes purification through column chromatography.
About
CAS No
84467-54-9
English Name
1-[1-(4-Chlorophenyl)cyclobutyl]-3-methyl-1-butanamine
Molecular Formula
C15H22ClN
Molecular Weight
251.8 g/mol
SMILES
CC(C)CC(C1(C2=CC=C(Cl)C=C2)CCC1)N
InChIKey
WQSACWZKKZPCHN-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
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