Compound Q&A
How is N-[4-(Trifluoromethoxy)phenyl]acetamide (CAS: 1737-06-0) typically synthesized?
Answer
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N-[4-(Trifluoromethoxy)phenyl]acetamide (CAS: 1737-06-0) is synthesized by reacting 4-(trifluoromethoxy)phenyl isocyanate with acetic acid in the presence of a base such as triethylamine. The process involves careful control of the reaction conditions to ensure high yield and selectivity. The use of a fume hood is recommended due to the potentially toxic nature of the reactants and products.
About
CAS No
1737-06-0
English Name
N-[4-(Trifluoromethoxy)phenyl]acetamide
Molecular Formula
C9H8F3NO2
Molecular Weight
219.16199999999995 g/mol
SMILES
CC(=O)NC1=CC=C(C=C1)OC(F)(F)F
InChIKey
QQRLAETWHFRNQH-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
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