Compound Q&A

How is [3-(2-Hydroxyethyl)phenyl]boronic acid (CAS: 647853-32-5) typically synthesized?

Answer

[3-(2-Hydroxyethyl)phenyl]boronic acid
[3-(2-Hydroxyethyl)phenyl]boronic acid is commonly synthesized via the Suzuki coupling reaction. The synthesis involves the reaction of phenyllithium with 2-hydroxyethyl boronic acid to form the boronic ester, which is then coupled with a halide or tosylate under palladium catalysis. This method provides good yields and high selectivity, making it a versatile route for this compound.

About

English Name [3-(2-Hydroxyethyl)phenyl]boronic acid
Molecular Formula C8H11BO3
Molecular Weight 165.98 g/mol
SMILES B(C1=CC(=CC=C1)CCO)(O)O
InChIKey GCSYFWQBJAJDGY-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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