Compound Q&A
How is [3-(2-Hydroxyethyl)phenyl]boronic acid (CAS: 647853-32-5) typically synthesized?
Answer
![[3-(2-Hydroxyethyl)phenyl]boronic acid](https://static.chemtradehub.com/structs/647/647853-32-5-c363.webp "[3-(2-Hydroxyethyl)phenyl]boronic acid")
[3-(2-Hydroxyethyl)phenyl]boronic acid is commonly synthesized via the Suzuki coupling reaction. The synthesis involves the reaction of phenyllithium with 2-hydroxyethyl boronic acid to form the boronic ester, which is then coupled with a halide or tosylate under palladium catalysis. This method provides good yields and high selectivity, making it a versatile route for this compound.
About
CAS No
647853-32-5
English Name
[3-(2-Hydroxyethyl)phenyl]boronic acid
Molecular Formula
C8H11BO3
Molecular Weight
165.98499999999999 g/mol
SMILES
B(C1=CC(=CC=C1)CCO)(O)O
InChIKey
GCSYFWQBJAJDGY-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
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