Compound Q&A
How is N-Fmoc-4-(tert-butoxycarbonylmethoxy)-L-phenylalanine (CAS: 181951-92-8) typically synthesized?
Answer
N-Fmoc-4-(tert-butoxycarbonylmethoxy)-L-phenylalanine is synthesized via the amide coupling of Fmoc-protected phenylalanine and tert-butoxycarbonylmethoxy-protected amino group. The reaction is catalyzed by a suitable coupling reagent like HOBt and DCC. The yield is typically around 75-80%, and the product is isolated by column chromatography.
About
CAS No
181951-92-8
English Name
N-Fmoc-4-(tert-butoxycarbonylmethoxy)-L-phenylalanine
Molecular Formula
C30H31NO7
Molecular Weight
517.58 g/mol
SMILES
CC(C)(C)OC(=O)COC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
InChIKey
HGZSQWKDOAHSLN-SANMLTNESA-N
Last Updated: 2025-11-01 18:55
