Compound Q&A
How is 2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine (CAS: 889447-20-5) typically synthesized?
Answer
![2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine](https://static.chemtradehub.com/structs/889/889447-20-5-03a0.webp "2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine")
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine is typically synthesized through a multi-step process involving the protection of a pyrazine ring, subsequent introduction of chlorine and iodine functionalities, and deprotection steps. Common synthetic methods include electrophilic aromatic substitution reactions and coupling reactions under mild or moderate conditions.
About
CAS No
889447-20-5
English Name
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine
Molecular Formula
C6H3ClIN3
Molecular Weight
279.47 g/mol
SMILES
C1=C(C2=NC(=CN=C2N1)Cl)I
InChIKey
JYAUQLBWOPEZFN-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55
![2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine — Shanghai Yinxin Laboratory Equipment Co., Ltd.](https://static.chemtradehub.com/suppliers/67cdd97a57537e5c8069adfb/67cdd97a57537e5c8069adfb-logo.webp){kind=logo}
![2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine — ShangHaiYiJiShengWuKeJiYouXianGongSiXiaoShouBu](https://static.chemtradehub.com/suppliers/67cecfe92b2de6e8e95a656d/67cecfe92b2de6e8e95a656d-logo.webp){kind=logo}
![2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}