Compound Q&A
How is N-(2-(2-(2-Methoxy-4-morpholinophenylamino)-5-fluoropyrimidin-4-ylamino)phenyl)methanesulfonamide (CAS: 1191911-26-8) typically synthesized?
Answer
N-(2-(2-(2-Methoxy-4-morpholinophenylamino)-5-fluoropyrimidin-4-ylamino)phenyl)methanesulfonamide is typically synthesized through a multi-step process involving the coupling of 5-fluoropyrimidine with a morpholine derivative, followed by the introduction of the methoxyphenyl moiety and sulfonamidation. The reaction is catalyzed by a suitable organic base and proceeds with high selectivity and good yield.
About
CAS No
1191911-26-8
English Name
N-(2-(2-(2-Methoxy-4-morpholinophenylamino)-5-fluoropyrimidin-4-ylamino)phenyl)methanesulfonamide
Molecular Formula
C22H25FN6O4S
Molecular Weight
488.5450000000003 g/mol
SMILES
COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F
InChIKey
XXHHOTZUJIXPJX-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
