Compound Q&A

How is 6-Methoxy-1H-indazol-5-amine (CAS: 749223-61-8) typically synthesized?

Answer

6-Methoxy-1H-indazol-5-amine
6-Methoxy-1H-indazol-5-amine is typically synthesized through a multi-step reaction involving the reaction of indole-3-carboxaldehyde with methanol in the presence of a suitable catalyst, such as p-toluenesulfonic acid. The reaction yields a high purity product with good selectivity and yield. Further purification can be achieved through recrystallization or column chromatography.

About

English Name 6-Methoxy-1H-indazol-5-amine
Molecular Formula C8H9N3O
Molecular Weight 163.18 g/mol
SMILES COC1=C(C=C2C=NNC2=C1)N
InChIKey GHEKVHASRAQCNU-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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