Compound Q&A

How is 1,3,5-Tri(thiophen-2-yl)benzene (CAS: 15509-95-2) typically synthesized?

Answer

1,3,5-Tri(thiophen-2-yl)benzene
1,3,5-Tri(thiophen-2-yl)benzene is typically synthesized via a multistep process involving thiolation of benzene followed by coupling reactions. Common synthetic methods include the Williamson ether synthesis using thiols and anhydrous bases. The reaction is highly selective, and the yield is usually around 80-90%. The synthesis requires careful temperature control and the use of anhydrous conditions to avoid side reactions.

About

CAS No 15509-95-2
English Name 1,3,5-Tri(thiophen-2-yl)benzene
Molecular Formula C18H12S3
Molecular Weight 324.5 g/mol
SMILES C1=CSC(=C1)C2=CC(=CC(=C2)C3=CC=CS3)C4=CC=CS4
InChIKey UBHPRZXDFVCNHZ-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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