Compound Q&A
How is 4-Methyl-2-(tributylstannyl)pyridine (CAS: 301652-23-3) typically synthesized?
Answer
4-Methyl-2-(tributylstannyl)pyridine is typically synthesized via a Grignard reaction or a Stille coupling reaction. The reaction involves the coupling of 4-methylpyridine with tributyltin bromide in the presence of a palladium catalyst, such as tetrakis(triphenylphosphine)palladium(0). The yield is usually around 70-80%, and the reaction is carried out under mild conditions in the presence of a base like cesium carbonate.
About
CAS No
301652-23-3
English Name
4-Methyl-2-(tributylstannyl)pyridine
Molecular Formula
C18H33NSn
Molecular Weight
382.18 g/mol
SMILES
CCCC[Sn](CCCC)(CCCC)c1cc(C)ccn1
InChIKey
SHMPGQWVDZTZBX-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59
