Compound Q&A

How is (2R)-3-(Dodecanoyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate (CAS: 20559-18-6) typically synthesized?

Answer

(2R)-3-(Dodecanoyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate
This compound is typically synthesized by reacting dodecanoic acid, 2-hydroxypropyl trimethylammonium chloride, and phosphorus pentoxide in the presence of a solvent like dimethylformamide. The reaction involves esterification and phosphorylation steps, yielding the target compound with good selectivity and high yield.

About

CAS No 20559-18-6
English Name (2R)-3-(Dodecanoyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate
Molecular Formula C20H42NO7P
Molecular Weight 439.5 g/mol
SMILES CCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)O
InChIKey BWKILASWCLJPBO-LJQANCHMSA-N
Last Updated: 2025-11-01 12:59

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