Compound Q&A

How is 5-Fluoro-2-hydroxybenzonitrile (CAS: 91407-41-9) typically synthesized?

Answer

5-Fluoro-2-hydroxybenzonitrile
5-Fluoro-2-hydroxybenzonitrile can be synthesized through the reaction of 2-hydroxybenzonitrile with fluorine in the presence of an appropriate catalyst, such as sulfuryl fluoride. The reaction is selective and yields a high percentage of the desired product. The process typically requires low temperatures and careful handling to avoid side reactions. The yield can be up to 90%, depending on the purity of the starting materials and reaction conditions.

About

CAS No 91407-41-9
English Name 5-Fluoro-2-hydroxybenzonitrile
Molecular Formula C7H4FNO
Molecular Weight 17.031 g/mol
SMILES C1=CC(=C(C=C1F)C#N)O
InChIKey MWLKQSIMPLORKX-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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