Compound Q&A
How is 1-{3-[4-(Diphenylmethyl)-1-piperazinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one (CAS: 60607-34-3) typically synthesized?
Answer
![1-{3-[4-(Diphenylmethyl)-1-piperazinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one](https://static.chemtradehub.com/structs/606/60607-34-3-0bd4.webp "1-{3-[4-(Diphenylmethyl)-1-piperazinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one")
1-{3-[4-(Diphenylmethyl)-1-piperazinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one is synthesized through multi-step organic synthesis involving the coupling of piperazine with diphenylmethanol, followed by condensation reactions. Common solvents include DMF, and the reaction is typically catalyzed by a strong acid or a suitable organic acid. The yield is around 70-80%, and the product is isolated by recrystallization.
About
CAS No
60607-34-3
English Name
1-{3-[4-(Diphenylmethyl)-1-piperazinyl]propyl}-1,3-dihydro-2H-benzimidazol-2-one
Molecular Formula
C27H30N4O
Molecular Weight
426.56 g/mol
SMILES
C1CN(CCN1CCCN2C3=CC=CC=C3NC2=O)C(C4=CC=CC=C4)C5=CC=CC=C5
InChIKey
BAINIUMDFURPJM-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
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