Compound Q&A
How is 1-(Bromomethyl)-4-(difluoromethoxy)benzene (CAS: 3447-53-8) typically synthesized?
Answer
1-(Bromomethyl)-4-(difluoromethoxy)benzene (CAS: 3447-53-8) is typically synthesized via a bromination reaction of 4-(difluoromethoxy)benzyl alcohol followed by further substitution. The reaction involves the use of N-bromosuccinimide (NBS) as a brominating agent and is performed in the presence of a suitable solvent like dichloromethane. The yield and selectivity of the reaction can be optimized with careful adjustment of reaction conditions.
About
CAS No
3447-53-8
English Name
1-(Bromomethyl)-4-(difluoromethoxy)benzene
Molecular Formula
C8H7BrF2O
Molecular Weight
237.04 g/mol
SMILES
C1=CC(=CC=C1CBr)OC(F)F
InChIKey
IFNMJBFIRKAQBT-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53
