Compound Q&A

How is Ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS: 115932-00-8) typically synthesized?

Answer

Ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate
Ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS: 115932-00-8) is typically synthesized through a multi-step process involving the condensation of pyrazolo[1,5-a]pyrimidine-3-carbonitrile with ethyl bromoacetate in the presence of a suitable base such as potassium carbonate. The reaction is usually carried out in an organic solvent like dimethylformamide (DMF) at room temperature. The yield is generally high, and the product is isolated by column chromatography followed by recrystallization from an appropriate solvent.

About

English Name Ethyl pyrazolo[1,5-a]pyrimidine-3-carboxylate
Molecular Formula C9H9N3O2
Molecular Weight 191.19 g/mol
SMILES CCOC(=O)c1cnn2cccnc12
InChIKey JEMAMNBFHPIPCR-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53

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