Compound Q&A

How is 1-(4-amino-2-chlorophenyl)ethan-1-one (CAS: 72531-23-8) typically synthesized?

Answer

1-(4-amino-2-chlorophenyl)ethan-1-one
1-(4-Amino-2-chlorophenyl)ethan-1-one (CAS: 72531-23-8) is synthesized via a multistep process starting from 2-chloroacetophenone and 4-aminophenol. The key steps involve the formation of an intermediate amide followed by selective chlorination and hydrolysis. This approach provides good yield and selectivity, making it a practical method for its synthesis.

About

CAS No 72531-23-8
English Name 1-(4-amino-2-chlorophenyl)ethan-1-one
Molecular Formula C8H8ClNO
Molecular Weight 169.61 g/mol
SMILES CC(=O)C1=C(C=C(C=C1)N)Cl
InChIKey SFWDKRVMIBKYQK-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53

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