Compound Q&A
How is Tegoprazan (CAS: 942195-55-3) typically synthesized?
Answer
Tegoprazan (CAS: 942195-55-3) is usually synthesized via a multi-step process involving alkylation, ring closure, and amidation reactions. Key steps include the use of tert-butyldimethylsilyl chloride as a protecting group, followed by ring formation using a condensation agent. The final amidation step uses sodium hydride and an amide to form the desired product with a high yield and selectivity.
About
CAS No
942195-55-3
English Name
Tegoprazan
Molecular Formula
C20H19F2N3O3
Molecular Weight
387.39 g/mol
SMILES
CC1=NC2=C(N1)C=C(C=C2OC3CCOC4=C3C(=CC(=C4)F)F)C(=O)N(C)C
InChIKey
CLIQCDHNPDMGSL-HNNXBMFYSA-N
Last Updated: 2025-10-31 17:33
