Compound Q&A

Are there alternatives to 2-(Trifluoromethyl)-1H-imidazole-4-carboxylic acid (CAS: 78016-98-5) in synthesis?

Answer

2-(Trifluoromethyl)-1H-imidazole-4-carboxylic acid
Several alternatives to 2-(Trifluoromethyl)-1H-imidazole-4-carboxylic acid exist in synthesis. Commonly used analogs include 2-fluoromethyl and 2,4-difluoromethyl imidazole derivatives. Isomers such as 1H-imidazole-4-carboxylic acid are also available. Alternative reagents like trifluoromethyl chlorides and imidazole derivatives can be used as substitutes in various synthetic processes, depending on the specific application and desired properties.

About

CAS No 78016-98-5
English Name 2-(Trifluoromethyl)-1H-imidazole-4-carboxylic acid
Molecular Formula C5H3F3N2O2
Molecular Weight 180.09 g/mol
SMILES C1=C(NC(=N1)C(F)(F)F)C(=O)O
InChIKey DQPSZGHYQKCZEY-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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