Compound Q&A
How is 6-Fluoro-2-mercaptobenzothiazole (CAS: 8006-85-7) typically synthesized?
Answer
6-Fluoro-2-mercaptobenzothiazole can be synthesized via the Friedel-Crafts alkylation of benzothiazole with fluoroacetic acid, followed by reduction of the acetylation group. Commonly, this involves the use of metallic sodium in liquid ammonia as a reducing agent. The yield is typically high, around 90%, and the method ensures good selectivity and reactivity.
About
CAS No
8006-85-7
English Name
6-Fluoro-2-mercaptobenzothiazole
Molecular Formula
C7H4FNS2
Molecular Weight
185.241762161255 g/mol
SMILES
S1C(NC2C=CC(=CC1=2)F)=S
InChIKey
XDZVUKOOUHIRKY-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
