Compound Q&A
How is 4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS: 744209-63-0) typically synthesized?
Answer
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4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine can be synthesized via the reaction of 4-chloropyrrolo[2,3-b]pyridine with phenylsulfonyl chloride in the presence of a base, such as triethylamine. The yield is typically around 70-80%, and the reaction is carried out in an inert solvent like dichloromethane. The reaction is selective and proceeds under mild conditions.
About
CAS No
744209-63-0
English Name
4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
Molecular Formula
C13H9ClN2O2S
Molecular Weight
292.75 g/mol
SMILES
C1=CC=C(C=C1)S(=O)(=O)N2C=CC3=C(C=CN=C32)Cl
InChIKey
ZWIKJILDMNXRAR-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
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