Compound Q&A

How is 8-Fluoroquinazoline-2,4(1H,3H)-dione (CAS: 959236-96-5) typically synthesized?

Answer

8-Fluoroquinazoline-2,4(1H,3H)-dione
8-Fluoroquinazoline-2,4(1H,3H)-dione can be synthesized through condensation of 8-fluoroquinazoline with acetic anhydride or other suitable reagents. The reaction is typically carried out under mild conditions in the presence of a catalyst like dicyclohexylcarbodiimide (DCC) or 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC). High yields and good selectivity are achieved under these conditions.

About

English Name 8-Fluoroquinazoline-2,4(1H,3H)-dione
Molecular Formula C8H5FN2O2
Molecular Weight 180.138 g/mol
SMILES C1=CC2=C(C(=C1)F)NC(=O)NC2=O
InChIKey FWGXKHUKBVXXCD-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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