Compound Q&A
How is 4-(2'-Bromomethyl)-1,3-dihydro-2H-indole-2-one (CAS: 120427-96-5) typically synthesized?
Answer
4-(2'-Bromomethyl)-1,3-dihydro-2H-indole-2-one can be synthesized through a bromination reaction of indole using N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction involves the introduction of a bromomethyl group onto the indole ring, leading to a high yield of the desired product.
About
CAS No
120427-96-5
English Name
4-(2'-Bromomethyl)-1,3-dihydro-2H-indole-2-one
Molecular Formula
C10H8BrNO
Molecular Weight
238.0806 g/mol
EINECS
1308068-626-2
SMILES
BrCCc1cccc2=NC(=O)C=c12
InChIKey
KEFXEJHKEJPEOB-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16
