Compound Q&A

How is 4-Phenylazepane (CAS: 73252-01-4) typically synthesized?

Answer

4-Phenylazepane
4-Phenylazepane is typically synthesized via a multistep process involving the condensation of a primary amine with a chloroarene followed by ring closure. Commonly, this involves the reaction of 2-phenylethanamine with chlorobenzene in the presence of a base like sodium hydroxide, followed by ring closure using a catalyst such as p-toluenesulfonic acid. The yield and selectivity can be improved by optimizing reaction conditions.

About

CAS No 73252-01-4
English Name 4-Phenylazepane
Molecular Formula C12H17N
Molecular Weight 175.27 g/mol
SMILES C1CC(CCNC1)C2=CC=CC=C2
InChIKey AHKQOPMYYACTFC-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23

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