Compound Q&A

How is (7R,8R,9S,13S,14S,17S)-13-Methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta[a]phenanthrene-3,17-diol (CAS: 153004-31-0) typically synthesized?

Answer

(7R,8R,9S,13S,14S,17S)-13-Methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta[a]phenanthrene-3,17-diol
This compound is typically synthesized via a multistep process involving the protection of key functional groups, introduction of the pentafluoropentyl thioether, and subsequent ring-opening reactions. The synthesis often employs catalytic hydrogenation and use of protecting agents to ensure the desired stereochemistry. High yields and good selectivity are achieved with optimized conditions and careful control of reaction parameters.

About

English Name (7R,8R,9S,13S,14S,17S)-13-Methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta[a]phenanthrene-3,17-diol
Molecular Formula C32H47F5O2S
Molecular Weight 590.78 g/mol
SMILES Oc1ccc2c(c1)C[C@H]([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2O)C)CCCCCCCCCSCCCC(C(F)(F)F)(F)F
InChIKey BVAUHWMMAVAPFK-LSVBPWPTSA-N
Last Updated: 2025-10-28 23:23

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