Compound Q&A
How is 5-Chloro-1,2,3,4-tetrahydroisoquinoline (CAS: 73075-43-1) typically synthesized?
Answer
5-Chloro-1,2,3,4-tetrahydroisoquinoline is usually synthesized via the reduction of 5-chloroisoquinoline followed by hydrogenation. The reaction typically involves palladium catalysts and requires conditions such as formic acid or hydrogen gas under pressure. The overall yield is moderate, and the method is selective for the desired product.
About
CAS No
73075-43-1
English Name
5-Chloro-1,2,3,4-tetrahydroisoquinoline
Molecular Formula
C9H10ClN
Molecular Weight
167.64 g/mol
SMILES
C1CNCC2=C1C(=CC=C2)Cl
InChIKey
OHOZWCJUZQXMAW-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15
