Compound Q&A

How is 3-(4-(Methylthio)phenyl)acrylic Acid (CAS: 102016-58-0) typically synthesized?

Answer

3-(4-(Methylthio)phenyl)acrylic Acid
3-(4-(Methylthio)phenyl)acrylic Acid (CAS: 102016-58-0) is synthesized through a multi-step process involving the condensation of 4-(methylthio)benzaldehyde with acryloyl chloride, followed by acid hydrolysis to form the carboxylic acid. The reaction typically uses a catalyst such as 4-(dimethylamino)pyridine (DMAP) and proceeds under mild conditions. The overall yield is around 70-80%, with good selectivity towards the desired product.

About

English Name 3-(4-(Methylthio)phenyl)acrylic Acid
Molecular Formula C10H10O2S
Molecular Weight 194.25 g/mol
SMILES CSC1=CC=C(C=C1)C=CC(=O)O
InChIKey AHBHKZCSIUIANZ-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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