Compound Q&A

How is Rebamipide 3-Chloro Impurity (CAS: 90098-05-8) typically synthesized?

Answer

Rebamipide 3-Chloro Impurity
Rebamipide 3-Chloro Impurity is synthesized through a multi-step process involving nucleophilic substitution reactions. Commonly, a starting material undergoes a halogenation step, followed by a condensation reaction with a secondary amine, leading to the formation of the 3-chloro impurity. The synthesis typically uses basic catalysts and requires careful control of reagent ratios to achieve high yields and selectivity.

About

CAS No 90098-05-8
English Name Rebamipide 3-Chloro Impurity
Molecular Formula C19H15ClN2O4
Molecular Weight 370.79 g/mol
SMILES C1=CC=C2C(=C1)C(=CC(=O)N2)CC(C(=O)O)NC(=O)C3=CC(=CC=C3)Cl
InChIKey BDWGQNMAAZVUQH-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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