Compound Q&A

How is Bis(biphenyl-4-yl)[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]amine (CAS: 952431-30-0) typically synthesized?

Answer

Bis(biphenyl-4-yl)[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]amine
Bis(biphenyl-4-yl)[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]amine (CAS: 952431-30-0) is synthesized via a multistep process involving boronic acid coupling reactions. The synthesis typically requires catalysis with palladium acetate and a base such as triphenylphosphine. The yield is around 70-80%, and the reaction is performed under inert atmosphere to avoid oxidation.

About

English Name Bis(biphenyl-4-yl)[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]amine
Molecular Formula C36H34BNO2
Molecular Weight 523.49 g/mol
SMILES B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)N(C3=CC=C(C=C3)C4=CC=CC=C4)C5=CC=C(C=C5)C6=CC=CC=C6
InChIKey PESBFNLGEMHNAM-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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