Compound Q&A

How is Methyl 5-bromo-1-benzofuran-2-carboxylate (CAS: 26028-36-4) typically synthesized?

Answer

Methyl 5-bromo-1-benzofuran-2-carboxylate
Methyl 5-bromo-1-benzofuran-2-carboxylate (CAS: 26028-36-4) is typically synthesized through the bromination of methyl 1-benzofuran-2-carboxylate using N-bromosuccinimide (NBS) in the presence of a radical initiator like azobisisobutyronitrile (AIBN). This method provides high selectivity and yield under suitable conditions.

About

CAS No 26028-36-4
English Name Methyl 5-bromo-1-benzofuran-2-carboxylate
Molecular Formula C10H7BrO3
Molecular Weight 255.07 g/mol
SMILES COC(=O)c1cc2cc(Br)ccc2o1
InChIKey ZZDBMDNRQQDSKG-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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