Compound Q&A

How is 1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid (CAS: 1125-29-7) typically synthesized?

Answer

1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid
1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid is synthesized by various methods, including Hofmann degradation of 1,3,5-trimethylpyrazine. Commonly, it involves the use of strong acids like sulfuric acid, with high yields and good selectivity. The reaction is typically carried out in a fume hood for safety reasons.

About

CAS No 1125-29-7
English Name 1,3,5-Trimethyl-1H-pyrazole-4-carboxylic acid
Molecular Formula C7H10N2O2
Molecular Weight 154.17 g/mol
SMILES CC1=C(C(=NN1C)C)C(=O)O
InChIKey NOIOGQJFLIPRBI-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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