Compound Q&A
How is (1S,3aR,6aS)-tert-Butyl octahydrocyclopenta[c]pyrrole-1-carboxylate oxalate (CAS: 907606-68-2) typically synthesized?
Answer
![(1S,3aR,6aS)-tert-Butyl octahydrocyclopenta[c]pyrrole-1-carboxylate oxalate](https://static.chemtradehub.com/structs/907/907606-68-2-ebd5.webp "(1S,3aR,6aS)-tert-Butyl octahydrocyclopenta[c]pyrrole-1-carboxylate oxalate")
(1S,3aR,6aS)-tert-Butyl octahydrocyclopenta[c]pyrrole-1-carboxylate oxalate is synthesized via a multi-step process. The key steps include the synthesis of the oxime from the corresponding carboxylic acid, followed by an intramolecular cyclization and oxalate esterification. Common solvents include dichloromethane and acetonitrile, with triethylamine as a base. The overall yield is around 70-80%, with good regioselectivity and stereoselectivity.
About
CAS No
907606-68-2
English Name
(1S,3aR,6aS)-tert-Butyl octahydrocyclopenta[c]pyrrole-1-carboxylate oxalate
Molecular Formula
C14H23NO6
Molecular Weight
301.34 g/mol
SMILES
CC(C)(C)OC(=O)C1C2CCCC2CN1.C(=O)(C(=O)O)O
InChIKey
ZCTXDLWZMFBZEV-PUBMXKGKSA-N
Last Updated: 2025-10-28 15:15
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