Compound Q&A

How is 5-Bromo-2-methyl-1H-indole (CAS: 1075-34-9) typically synthesized?

Answer

5-Bromo-2-methyl-1H-indole
5-Bromo-2-methyl-1H-indole is commonly synthesized via alkylation of indole followed by bromination. The alkylation step often uses methyl iodide as the alkylating agent in the presence of a base like sodium hydride. Bromination is typically carried out using bromine in the presence of a Lewis acid catalyst, such as aluminum bromide, to ensure high yield and selectivity.

About

CAS No 1075-34-9
English Name 5-Bromo-2-methyl-1H-indole
Molecular Formula C9H8BrN
Molecular Weight 210.07 g/mol
SMILES CC1=CC2=C(N1)C=CC(=C2)Br
InChIKey BJUZAZKEDCDGRW-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

Related Q&A

Compound Q&A

What are the physical and chemical properties of 5-Bromo-2-methyl-1H-indole (CAS: 1075-34-9)?

5-Bromo-2-methyl-1H-indole is a crystalline solid with a molecular weight of approximately 219.03 g/...

Compound Q&A

What industries use 5-Bromo-2-methyl-1H-indole (CAS: 1075-34-9)?

5-Bromo-2-methyl-1H-indole is used in various industries, particularly in the pharmaceutical sector ...

Compound Q&A

What precautions should be taken when handling 5-Bromo-2-methyl-1H-indole (CAS: 1075-34-9)?

When handling 5-Bromo-2-methyl-1H-indole, it is essential to wear appropriate personal protective eq...

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...