Compound Q&A
How is 2-Bromo-5-nitropyridine-4-carboxylic acid (CAS: 1053655-82-5) typically synthesized?
Answer
2-Bromo-5-nitropyridine-4-carboxylic acid is typically synthesized by bromination of 5-nitropyridine-4-carboxylic acid. This process involves treating the acid with bromine in the presence of a suitable base like sodium hydroxide. The reaction is carried out in an aprotic solvent, and the yield is generally around 70-80%. Catalytic amounts of a strong base can improve selectivity and yield.
About
CAS No
1053655-82-5
English Name
2-Bromo-5-nitropyridine-4-carboxylic acid
Molecular Formula
C6H3BrN2O4
Molecular Weight
247.0030 g/mol
SMILES
C1=C(C(=CN=C1Br)[N+](=O)[O-])C(=O)O
InChIKey
YISYYAZCRUHFBZ-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54
