Compound Q&A

How is Methyl (2-aminophenyl)acetate (CAS: 35613-44-6) typically synthesized?

Answer

Methyl (2-aminophenyl)acetate
Methyl (2-aminophenyl)acetate (CAS: 35613-44-6) is synthesized via a condensation reaction between 2-aminophenol and acetic anhydride. The reaction proceeds under mild conditions in the presence of a catalytic amount of a Lewis acid, such as aluminum chloride, to selectively form the desired ester. The yield is typically around 70-80%, and the product can be purified by recrystallization from a suitable solvent.

About

CAS No 35613-44-6
English Name Methyl (2-aminophenyl)acetate
Molecular Formula C9H11NO2
Molecular Weight 165.19 g/mol
SMILES COC(=O)CC1=CC=CC=C1N
InChIKey BWQBYHGDMBHIIQ-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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