Compound Q&A
How is 1-(4-fluorophenyl)cyclobutane-1-carbonitrile (CAS: 405090-30-4) typically synthesized?
Answer
1-(4-fluorophenyl)cyclobutane-1-carbonitrile can be synthesized by the reaction of 4-fluorophenylacetonitrile with a reducing agent such as sodium borohydride. The reaction typically proceeds with high selectivity and yields around 85-90%. The process involves stirring the mixture under an inert atmosphere and monitoring the reaction progress with TLC or GC.
About
CAS No
405090-30-4
English Name
1-(4-fluorophenyl)cyclobutane-1-carbonitrile
Molecular Formula
C11H10FN
Molecular Weight
164.22 g/mol
SMILES
C1CC(C1)(C#N)C2=CC=C(C=C2)F
InChIKey
GXRILDIAHADHNS-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54
