Compound Q&A

How is 6-Bromo-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]-1-piperazinyl}-2-[4-(4-methyl-1-piperazinyl)phenyl]-1H-imidazo[4,5-b]pyridine (CAS: 1095382-05-0) typically synthesized?

Answer

6-Bromo-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]-1-piperazinyl}-2-[4-(4-methyl-1-piperazinyl)phenyl]-1H-imidazo[4,5-b]pyridine
This compound is synthesized using a multi-step process involving coupling reactions, alkylation, and condensation. Commonly, it uses catalysts like palladium and ligands. The yield is moderate to high, depending on the purity of intermediates. The synthetic route involves the use of 5-methyl-1,2-oxazole and piperazines as key starting materials.

About

English Name 6-Bromo-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]-1-piperazinyl}-2-[4-(4-methyl-1-piperazinyl)phenyl]-1H-imidazo[4,5-b]pyridine
Molecular Formula C26H31BrN8O
Molecular Weight 551.49 g/mol
SMILES Cc1cc(no1)CN2CCN(CC2)c3c(cnc4c3[nH]c(n4)c5ccc(cc5)N6CCN(CC6)C)Br
InChIKey GFLQCBTXTRCREJ-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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