Compound Q&A
How is 3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid (CAS: 1450754-37-6) typically synthesized?
Answer
![3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid](https://static.chemtradehub.com/structs/145/1450754-37-6-ab1f.webp "3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid")
3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid can be synthesized via a multi-step process involving the diazirination of propionic acid, followed by the addition of 3-butyn-1-yl moiety using a Grignard reagent. The process requires careful control of reaction conditions to achieve high yield and selectivity, often involving protective groups and purification steps.
About
CAS No
1450754-37-6
English Name
3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid
Molecular Formula
C8H10N2O2
Molecular Weight
16.04 g/mol
SMILES
C#CCCC1(N=N1)CCC(=O)O
InChIKey
JRNSKSYASHYNCM-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54
![3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid — ShangHaiMaiRuiErShengHua Technology Co Ltd](https://static.chemtradehub.com/suppliers/67ced3b52b2de6e8e95a6e52/67ced3b52b2de6e8e95a6e52-logo.webp){kind=logo}
![3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![3-[3-(3-Butyn-1-yl)-3H-diaziren-3-yl]propanoic acid — Jin Jinle (Hunan) Chemical Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}