Compound Q&A

Are there alternatives to (R)-Apremilast (CAS: 608141-44-2) in synthesis?

Answer

(R)-Apremilast
In the synthesis of (R)-Apremilast (CAS: 608141-44-2), chemists may explore using enantiopure or racemic precursors. Common alternatives include the use of chiral pool compounds or asymmetric synthesis methodologies. Additionally, synthetic routes may involve using achiral reagents and employing chiral auxiliary strategies for enantioselective synthesis.

About

English Name (R)-Apremilast
Molecular Formula C22H24N2O7S
Molecular Weight 460.51 g/mol
SMILES CCOc1cc(ccc1OC)[C@@H](N1C(=O)c2c(C1=O)c(ccc2)NC(=O)C)CS(=O)(=O)C
InChIKey IMOZEMNVLZVGJZ-KRWDZBQOSA-N
Last Updated: 2025-10-27 07:45

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