Compound Q&A

Are there alternatives to 2-Fluoro-5-(trifluoromethoxy)benzonitrile (CAS: 886498-08-4) in synthesis?

Answer

2-Fluoro-5-(trifluoromethoxy)benzonitrile
Alternatives to 2-Fluoro-5-(trifluoromethoxy)benzonitrile (CAS: 886498-08-4) in synthesis include 2-Chloro-5-(trifluoromethoxy)benzonitrile and 2-Iodo-5-(trifluoromethoxy)benzonitrile, which can serve similar functional group requirements but with different reactivity profiles. Other common reagents, such as 2-Bromo-5-(trifluoromethoxy)benzonitrile, can also be considered as substitutes depending on the specific synthetic route.

About

English Name 2-Fluoro-5-(trifluoromethoxy)benzonitrile
Molecular Formula C8H3F4NO
Molecular Weight 17.031 g/mol
SMILES C1=CC(=C(C=C1OC(F)(F)F)C#N)F
InChIKey MFLGNKVMGUFLOV-UHFFFAOYSA-N
Last Updated: 2025-10-27 07:45

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