What regulatory guidelines apply to Methyl 3-nitroisonicotinate (CAS: 103698-10-8)?

Methyl 3-nitroisonicotinate (CAS: 103698-10-8) is classified under the Globally Harmonized System (GHS) as a skin and eye irritant. It falls under the European Union's REACH regulation, which requires manufacturers and importers to register substances above 1 tonne per year. Additionally, the FDA regulates its use in food additives, and the EPA oversees its use in pesticides. Compliance with these regulations is essential for safe handling and use.