Compound Q&A

How is 3-Fluoro-5-hydroxybenzoic acid (CAS: 860296-12-4) typically synthesized?

Answer

3-Fluoro-5-hydroxybenzoic acid
3-Fluoro-5-hydroxybenzoic acid can be synthesized through the protection and subsequent deprotection of 5-hydroxybenzoic acid. This involves protecting the carboxylic acid group with a suitable reagent, followed by introducing a fluoro group using fluorination techniques. Common methods include nucleophilic substitution or electrophilic aromatic substitution strategies, with yield typically around 70-80%.

About

English Name 3-Fluoro-5-hydroxybenzoic acid
Molecular Formula C7H5FO3
Molecular Weight 156.11 g/mol
SMILES OC(=O)c1cc(O)cc(F)c1
InChIKey PYZWGHVZOQTMCW-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:39

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