Compound Q&A

How is 4-(4-Bromophenyl)-2,6-diphenylpyrimidine (CAS: 58536-46-2) typically synthesized?

Answer

4-(4-Bromophenyl)-2,6-diphenylpyrimidine
4-(4-Bromophenyl)-2,6-diphenylpyrimidine is typically synthesized via a multi-step process involving bromination and coupling reactions. Commonly, the bromination of a suitable starting material followed by a Heck-type or Suzuki coupling with phenylboronic acid yields the target compound. This synthesis involves the use of palladium catalysts and is known for its high yield and selectivity.

About

CAS No 58536-46-2
English Name 4-(4-Bromophenyl)-2,6-diphenylpyrimidine
Molecular Formula C22H15BrN2
Molecular Weight 387.28 g/mol
SMILES BrC1=CC=C(C2=NC(C3=CC=CC=C3)=NC(C4=CC=CC=C4)=C2)C=C1
InChIKey GHDBFGUOBVYEOV-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:39

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