How is 2-Amino-4-(2-methyl-2-propanyl)benzoic acid (CAS: 728945-64-0) typically synthesized?

2-Amino-4-(2-methyl-2-propanyl)benzoic acid can be synthesized through a multi-step process. A common method involves the reaction of 2-methyl-2-propanol with benzoic anhydride followed by the addition of excess ammonia to form the amino derivative. The reaction is typically conducted under basic conditions, and the product is isolated by crystallization. Catalysts like sodium hydroxide may be used to enhance reactivity and selectivity.