Compound Q&A

How is Ethyl 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate (CAS: 94242-51-0) typically synthesized?

Answer

Ethyl 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate
Ethyl 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate (CAS: 94242-51-0) is typically synthesized via the alkylation of 6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid with cyclopropylmethyl iodide in the presence of a Lewis acid catalyst, such as aluminum trichloride, to achieve a high yield of the desired product.

About

CAS No 94242-51-0
English Name Ethyl 1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylate
Molecular Formula C15H12F3NO3
Molecular Weight 311.26 g/mol
SMILES CCOC(=O)c1cn(c2c(c1=O)cc(c(c2F)F)F)C3CC3
InChIKey FGICMAMEHORFNK-UHFFFAOYSA-N
Last Updated: 2025-10-26 09:38

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